2019 JUL 16 (NewsRx) -- By a News Reporter-Staff News Editor at Chemicals & Chemistry Daily Daily -- Research findings on Chemistry - Analytical Chemistry are discussed in a new report. According to news originating from Hefei, People’s Republic of China, by NewsRx correspondents, research stated, “Direct chemical profiling and protein identification from living single cells using mass spectrometry (MS) have been demonstrated to further our understanding of biological variability and differential susceptibility to several diseases and treatments. Despite the great challenge from extremely complicated cytoplasm, we recently proposed a versatile MS strategy to achieve direct mass spectrometric characterization of both proteins and metabolite-like small molecules directly from living cells or single cells.”
Financial supporters for this research include Ministry of Education of the People’s Republic of China, National Natural Science Foundation of China, Recruitment Program of Global Experts, Development Foundation, Hefei Center for Physical Science and Technology.
Our news journalists obtained a quote from the research from the University of Scienceand Technology, “Although the capability to directly handle cell cytoplasm was presumably attributed to microelectrophoresis in our previous studies, the assumption had only been partially explored by some preliminary experiments. To better understand the mechanism, herein, we systematically characterized its separation behavior with a series of model compounds covering a wide range of molecular size.”
According to the news editors, the research concluded: “With the merit of in situ separation, microelectrophoresis herein has been further demonstrated as an attractive and alternative tool, which can potentially contribute to direct MS measurements of more protein interactions or metabolic pathways in living single cells or a few cells.”
For more information on this research see: Ultrafast Microelectrophoresis: Behind Direct Mass Spectrometry Measurements of Proteins and Metabolites in Living Cell/Cells. Analytical Chemistry, 2019;():. Analytical Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Analytical Chemistry - http://www.pubs.acs.org/journal/ancham)
The news correspondents report that additional information may be obtained from Y. Chen, Hefei National Laboratory for Physical Sciences at the Microscale, School of Chemistry and Materials Science, University of Science and Technology of China, 230026 Hefei, People’s Republic of China. Additional authors for this research include G. Li, S. Yuan, Y. Pan, Y. Liu and G. Huang.
The direct object identifier (DOI) for that additional information is: https://doi.org/10.1021/acs.analchem.9b00716. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
The publisher’s contact information for the journal Analytical Chemistry is: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA.
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MarketScreener, 2019-07-16, https://www.marketscreener.com/LIVING-CELL-TECHNOLOGIES-10353909/news/Studies-from-University-of-Science-and-Technology-Yield-New-Information-about-Analytical-Chemistry--28913208/
On May 11, the Nature Publishing Group released Nature Publishing Index 2010 China, remarking “a dramatic rise in the quality of research being published by China”. University of Science and Technology of China is ranked 3rd of TOP 10 Institutions in Index 2010 China.
This article came from News Center of USTC.