A circadian clock is a biochemical oscillator essential for biological phenomena and metabolic control. In 2017, the Nobel Prize in Physiology or Medicine was awarded to three scientists for their discoveries of molecular mechanisms controlling the circadian rhythm in fruit flies. In her report, Prof. Susan S. Golden introduces the discovery and identification of circadian clock of cyanobacteria and the molecular mechanism controlling the circadian rhythm in cyanobacteria. The cyanobacterium builds a circadian clock on an oscillator composed of proteins KaiABC, which can recapitulate a circadian rhythm of KaiC phosphorylation. The cyanobacterial clock is composed of a novel post-translational oscillator coupled with a reinforcing transcription-translation oscillation, a redox-sensing input pathway, and a global output pathway that controls the genome through changes in DNA topology.
After the reports, Prof. Susan S. Golden and Prof. James W. Golden reply the questions raised by teachers and students .Also,they make a profound discussion on relevant academic problems. The atmosphere of the forum keeps warm and students find enormous benefits from it.
Question and answer session
The forum is hosted by Prof. ZHOU Congzhao of the School of Life Sciences of USTC.
(Written by YANG Ziyi，edited by YANG Xinqi, USTC News Center )
On May 11, the Nature Publishing Group released Nature Publishing Index 2010 China, remarking “a dramatic rise in the quality of research being published by China”. University of Science and Technology of China is ranked 3rd of TOP 10 Institutions in Index 2010 China.
This article came from News Center of USTC.