Researchers used magnetic nanoclusters to immobilize bacteriophages and pull them into biofilms where they killed the harmful bacteria.
Magnetic nanoparticle clusters have the power to punch through biofilms to reach bacteria that can foul water treatment systems, according to scientists at Rice University and the University of Science and Technology of China.
Biofilms can be beneficial in some wastewater treatment or industrial fermentation reactors owing to their enhanced reaction rates and resistance to exogenous stresses. In the present study, researchers used magnetic nanoclusters to immobilize bacteriophages and pull them into biofilms where they killed the harmful bacteria.
The phages were combined with nanoclusters of carbon, sulfur and iron oxide that were further modified with amino groups. The amino coating prompted the phages to bond with the clusters head-first, which left their infectious tails exposed and able to infect bacteria.
The lab is working on phage “cocktails” that would combine multiple types of phages and antibiotics with the particles to inhibit resistance.
On May 11, the Nature Publishing Group released Nature Publishing Index 2010 China, remarking “a dramatic rise in the quality of research being published by China”. University of Science and Technology of China is ranked 3rd of TOP 10 Institutions in Index 2010 China.
This article came from News Center of USTC.